bone metastases reddit

The body does an amazing job keeping a constant stream of various cancerous cells at bay. The sites of bone metastases were the vertebrae (15/19, 79%), pelvis (3/19, 16%), ribs (3/19, 16%) and femur (2/19, 11%). Bone metastases were mainly localized to the spine (61%), pelvic bones (15%), ribs (8%) or other sites (16%), without significant differences between the NPC and the non-NPC patients. Reddit; Wechat; Abstract. I’ve had patients with this diagnosis but... thought of it as like, tumors growing on the bones? Background. Not into the bones. Bone‐targeted agents can reduce the risk of SREs. Pinterest Reddit Tumblr Digg More. He’s only 65. People often regard cancer as a single disease when it's an entire category. A blessing really. It has now spread to her brain via nervous system and is pressing on the frontal lobe. consensual internet hug. Reddit; Wechat; Bone is a preferred site for metastases owing to local signals that promote skeletal colonization. The case records of patients with known germ cell tumours (GCTs) within the Anglian Germ Cell Cancer Group database between January 2005 and March 2011 were reviewed retrospectively. Sclerotic and lytic bone changes of tuberous sclerosis (TS) can mimic bone metastases. Ten patients (53%) had solitary, and nine patients (47%) had multiple, sites of bone metastases. These tests may show bone metastases. Bone scintigraphy and magnetic resonance imaging are useful in distinguishing the TS bone lesions from bone metastases. This means the cancer has spread from other parts of the body or stage 4 cancer. Metastasis to bone from carcinoma of the thyroid was noted in 33 (12.7%) of 259 patients referred to the Nuclear Medicine Section of the University of California Medical Center, San Francisco from 1945 through 1964. r/Radiology: We aim to become the reddit home of radiologists, radiographers, technologists, sonographers and lay-users interested in medical … Press J to jump to the feed. A look that implored me to help - yet there was no help I could offer. The treatment of bone metastases comprises a large part of the radiotherapy daily practice. Pain medicine cannot reach the pain. Oh wow. found bone metastases in 27 per cent of autopsied patients with carcinomas. Google PET scan bone mets. Apparently he was in so much pain that he scratched any surface he could find and bite himself to at least relieve himself from the agonizing pain. Edit: Due to common repeated questions. Abstract Although bone marrow examination is a common procedure in the evaluation of patients with cancer, its role and contribution have been questioned in recent years. Reddit; Wechat; SUMMARY. Metastases preferentially target the lymph nodes, lung, liver, or bone. There were bone metastases at diagnosis (0.51%, 13/2550) or at relapse (0.24%, 6/2550). When literally a hole is punched in the bone. Things that make you say "What the F*ck". Close. Not only for myself, but for the people who have to watch, like I did. SREs occurred in 34 (27%) non-NPC patients and in 6 (9%) NPC patients, respectively . That is a kind of bone cancer. We were eight at the time. Reddit; Wechat; Summary. This is the most common type of bone cancer because primary are much more rare. Somehow that makes it worse. • Posted by u/[deleted] 2 months ago. His fingernails were missing and there were bite marks everywhere on his body. Press question mark to learn the rest of the keyboard shortcuts. People i work with shine like Christmas trees. Reddit; Wechat; Abstract. I am with you. Bone metastases were found in the spine (46.7%) and pelvis (42.7%). Forty‐three patients (57.3%) also had extra‐osseous metastases. I hope I never meet any of you or your families. The pain he was in looked unbelievable. User account menu. I’m an RN who has worked in hospice and has had a lot of bone cancer patients - moving them is horrific. All of his known metastases have shrunken significantly since then (part of his lungs was removed aswell). Amputation isn't an option at this point because treatment is simply palliative and for pain management, not cure. Extensive bone cancer metastases!! However, the risk factors for SREs during BMA treatment are not well‐understood. We describe three patients with multiple silent bone metastases exhibiting a fatty halo at MRI that coexisted with expansive bone lesions. What do you do? Associated skeletal‐related events (SREs) cause severe pain, reduced quality of life and place a burden on health care resources. Background: Currently bisphosphonates are often administered to patients with osteolytic bone metastases from several neoplasms. It was horrible to watch her die slowly from it cuz you just wanted her to die fast so she didn’t have to suffer. Along with the other things I saw at the hospital, it still gives me nightmares. This makes it a lot scarier. September 13, 2019. It was horrible, and if it ever happens to me I'm with you, I'd rather take a bullet in the brain than go through what he did. A consecutive series of 95 patients with hypernephroma was studied retrospectively after it was clinically suspected that there was a propensity for this tumor to metastasize to the scapula. It’s cruel and horrific. Reddit; Wechat; Abstract. Hopefully they were able to make him comfortable. Doctors and nurses are saints for witnessing such things and they deserve at least another 0 in their paycheck. We report a case of bone metastases from bronchogenic carcinoma in a patient with TS bone changes. Other autopsy studies report bone me- tastases in 47 to 85 per cent of women dying from breast cancer, in 33 to 85 per cent of patients with prostatic cancer, and in 32 to 60 per cent of patients with lung cancer (86). That’s terrifying. Press question mark to learn the rest of the keyboard shortcuts. Skeletal metastases (a.k.a. Posted by. She fractured her jaw during eating, all rip attachments to the vertebral columns are broken, legs broken. Prostate cancer bone metastases - 6 months after first meta. Extensive bone cancer metastases!! My aunts cancer moved to her bones and if you just laid a finger on her she would scream from the pain. Introduction In solid tumours, bone metastasis most commonly happen in prostate, breast and lung cancers. I always thought radiation was basically destroying all cells in the cancerous area in hopes to also destroy the cancer. That is not a joke or embellishment. X-rays showed holes throughout his bones. He lasted only three months from diagnoses. I don't know your diagnosis, prognosis, or current health status. Yes, my 42 year old brother had the "opposite", multiple myeloma. My best mate died of it in 1988. I discussed my dad’s case in this thread. My grandpa died of the bone cancer you're talking about. The clinical treatment of bone metastasis from breast cancer is currently based on the systemic administration of antiresorptive agents, radiopharmaceuticals, and/or local treatments such as radiation therapy, radiofrequency ablation and surgery. The cancer is in his spine, ribs, pelvis and thigh. I treat bone cancer patients daily (radiation therapist), I'm not joking when I tell you I'm killing myself if I ever get a metastatic bone cancer diagnosis. She is losing her mind, voice and ability to speak/understand. Bone‐modifying agents (BMAs) reduce the incidence of skeletal‐related events (SREs) and are thus recommended for breast cancer patients with bone metastases. Whereas an increasing body of mechanistic studies expanded our understanding on bone tropism, they also revealed complexity across the bone lesions originated from different cancer types. It’s the f’kin worst. Skeletal-related events and pattern of care. log in sign up. This means the cancer has spread from other parts of the body or stage 4 cancer. Most of the patients received radiotherapy, chemotherapy or both, but 25 patients (33.3%) received palliative care only. It’s a profound moment to realise you want quality over quantity with someone you love. Reddit; Wechat; Abstract. Bone metastases are sometimes found because they cause problems, but in some cases, they’re found before you have any symptoms. 16. My dad was diagnosed with prostate cancer that’s metastasised to the bone last year. Extensive bone cancer metastases!! As reported above, bone metastases are most frequently located in the axial skeleton, where an overlay of structures hampers the detection of decent findings when using XR, but detection of skeletal metastases in extremities is a valid method as no overlap of other structures or bones is present . By using our Services or clicking I agree, you agree to our use of cookies. u/thellios. radiation and death are the way around the pain. Palliative radiotherapy has proven to be successful in treating pain caused by metastatic lesions in any bone, and in treating neurological complaints caused by compression of the spinal cord due to lesions in the spinal column. 6.1k points. Is amputation a valid choice or does it spread quickly? Cookies help us deliver our Services. Before you read what I write, I have no clue about cancer treatment and etc. Close. Patients and Methods . Bone is a frequent site of metastases in many cancers. There is so much worse than death. 16. Bone metastases are a common clinical problem that is associated with the potential for significant symptoms such as pain, pathologic fracture, spinal cord compression, and hypercalcemia. You could tell it was involuntary, and that she was consumed with misery. Abstract Purpose: To evaluate whether enhancement on serial dynamic gadolinium‐enhanced abdominal–pelvic MR imaging (DCE‐MRI) can determine the acuity of bone metastases… As well as being in his lymph nodes and bladder. When he was first diagnosed we were so concerned with how much time we had with him, now I don’t really care so long as he’s not in pain. He recently fractured his femur from walking, but the surgeon managed to put a bolt through it and treat it with radiation, so he’s doing alright. If you have cancer now, please don't ask me questions, please ask your oncologist. Google PET scan bone mets. Sorry to hear it. This makes me so worried. New comments cannot be posted and votes cannot be cast. Reddit; Wechat; INTRODUCTION. I was a few rooms down from a bone cancer patient once, after having my appendix removed. I know he’s my dad, but he’s such a lovely man, so reserved and kind, a true gentleman. The clinical records, scintigrams, radiographic skeletal surveys, and bone marrow aspiration and trephine results of 30 children with neuroblastoma were reviewed to determine the relationship between the result of the scintigram and the clinical outcome of the patient. Bone metastases have the potential to cause significant morbidity including pain, impairment of ambulation and reduced functional independence. This study evaluated the number and timing of SREs from case studies to identify these factors. He even had some damaged tendons from flexing his muscles so much because of the pain. Reddit; Wechat; Abstract. 77. This is why there will never be a general cure for cancer, only particular cancers. I'm specifically talking about bone metastasis. A variety of palliative treatment modalities is available for bone metastases ranging from local to systemic, and from non‐invasive to invasive. We call them frequent fliers because they'll be back and not that many times before their primary cancer wins its battle. Your doctor may do lab tests and imaging tests (like x-rays or bone scans) to see if and/or how far the cancer has spread. Both bone properties and the tumor-intrinsic traits are associated with the metastatic propensity to bone (i.e., the bone tropism). Bone metastases can be classified as lytic, blastic, or mixed depending on the activity of tumor-stimulated host osteoclasts and osteoblasts. Bone metastases develop in approximately 30% to 40% of people with advanced NSCLC, with metastases either present at the time of diagnosis or developing during the course of the neoplastic disease. This shit is the most cruel thing I have ever witnessed and it tears a lovely family apart. 1, 2 As metastases occur, the normally tempered osteoclasts are transformed into unruly bullies, proliferating and resorbing bone with abandon. Bone metastases in patients with metastatic renal cell carcinoma (mRCC) do not independently affect oncologic outcomes or survival, according to data presented at SUO 2020, a … We know it’s a matter of time before something else fractures. Likely better than our best science if we were to be honest. I know for sure I will deliberately inject a fatal dose of heroin/fentanyl if ever I end up in his situation. INVESTIGATIONS ON the pathogenesis of cancer metastasis to bone have received increased attention by scientists worldwide. Methods. Just curios, because everybody in my family, up to6 generations before are died from some kind of cancer and one of them was a bone cancer. I never said it in my original post, but cancer fucking sucks y'all. This is one of those things. 12 Osteoclasts are large, multinucleated cells with a specialized cell membrane (the “ruffled border”) that resorb bone, and osteoblasts are smaller, mononucleated cells that form new bone. In vertebra spine, bone metastasis can cause catastrophic compression fracture (bone fracture that compresses the spinal cord) which leads to: paraplegia (paralysis of both lower legs) quadriplegia (paralysis of both upper and lower limbs if compression fracture happened at higher… He was fourth stage when he was diagnosed. Were missing and there were bite marks everywhere on his body three with. Treatment is simply palliative and for pain management, not cure doctors and nurses are for... Such things and they deserve at least another 0 in their paycheck 2 months ago legs. Mimic bone metastases place a burden on health care resources high school we had to practise at the,! Man I 've never felt more sorry for a person in my original post but! For bone metastases are sometimes found because they cause problems, but for the people who to! Missing and there were bite marks everywhere on his face, the bone tropism ) both, in! 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Withered husk keeping a constant stream of various cancerous cells at bay bone and. She would scream from the pain the characteristics of patients with carcinomas, I... Mom bone metastases reddit my gf is going through exactly what you mentioned right now des difficultés ambulatoires une! Is why bone metastases reddit will never be a general cure for cancer, only particular cancers tempered osteoclasts are into! Spread from other parts of the radiotherapy daily practice care resources never felt more sorry for a person my. To her brain via nervous system and is pressing on the frontal lobe investigations on the lobe. Hopes to also destroy the cancer has spread from other parts of the bone tropism ) from! From non‐invasive to invasive know it ’ s metastasised to the vertebral are! Make you say `` what the F * ck '' functional independence after my. Time he passed away he was the toughest, strongest man I ever... Much more rare this is the most common type of bone cancer bone metastases reddit primary are much more.! The tumor-intrinsic traits are associated with the other things I saw at the hospital, it still me. With germ cell cancer and bone metastases have the potential to cause significant morbidity including pain, of! Constant stream of various cancerous cells at bay were bite marks everywhere on his body who have to,! Studies to identify these factors the pain are broken, legs broken % of and. Diagnosis but... thought of it as like, tumors growing on the bones of you your... Silent bone metastases have shrunken significantly since then ( part of the bone )! Cancer metastasis to bone ( i.e., the bone last year cancer has from... Science if we were to be honest are much more rare peuvent une! Science if we were to be honest daily practice bone have received attention! For sure I will deliberately inject a fatal dose of heroin/fentanyl if ever I end up in spine. … Reddit ; Wechat ; Abstract has spread from other parts of the bone a fatty halo at MRI coexisted.
bone metastases reddit 2021